CobaltMaghrebV1, Main, Exploration, bibRecord, 000226

Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests

Identifieur interne : 000226 ( Main/Exploration ); précédent : 000225; suivant : 000227

Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests

Auteurs : Messaouda Khallef [Algérie] ; Recep Liman [Turquie] ; Muhsin Konuk [Turquie] ; Brahim Hakk Ci Erci [Turquie] ; Djameleddine Benouareth [Algérie] ; Mouna Tabet [Algérie] ; Ahlem Abda [Algérie]

Source :

Cytotechnology [ 0920-9069 ] ; 2013.

RBID : PMC:4329306

Abstract

Genotoxic effects of bromoform and chloroform, disinfection by-products of the chlorination of drinking water, were examined by using mitotic index (MI), mitotic phase, chromosome aberrations (CAs) and comet assay on root meristematic cells of Allium cepa. Different concentrations of bromoform (25, 50, 75 and 100 μg/mL) and chloroform (25, 50, 100 and 200 μg/mL) were introduced to onion tuber roots. Distilled water was used as a negative control and methyl methansulfonate (MMS-10 μg/mL) as positive control. All obtained data were subjected to statistical analyses by using SPSS 15.0 for Windows software. For comparison purposes, Duncan multiple range tests by using one-way analysis of variance were employed and p < 0.05 was accepted as significant value. Exposure of both chemicals (except 25 μg/mL applications of bromoform) significantly decreased MI. Bromoform and chloroform (except 25 μg/mL applications) increased total CAs in Allium anaphase-telophase test. A significant increase in DNA damage was also observed at all concentrations of both bromoform and chloroform examined by comet assay. The damages were higher than that of positive control especially at 75–100 μg/mL for bromoform and 100–200 μg/mL for chloroform.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329306

DOI: 10.1007/s10616-013-9675-y
PubMed: 24363168
PubMed Central: 4329306

Affiliations:

Algérie, Turquie

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both <italic>Allium</italic>
 anaphase-telophase and comet tests</title>
<author><name sortKey="Khallef, Messaouda" sort="Khallef, Messaouda" uniqKey="Khallef M" first="Messaouda" last="Khallef">Messaouda Khallef</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1">Biochemistry Department, Faculty of Sciences, Badji Mokhtar University, 23000 Annaba, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biochemistry Department, Faculty of Sciences, Badji Mokhtar University, 23000 Annaba</wicri:regionArea>
<wicri:noRegion>23000 Annaba</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liman, Recep" sort="Liman, Recep" uniqKey="Liman R" first="Recep" last="Liman">Recep Liman</name>
<affiliation wicri:level="1"><nlm:aff id="Aff2">Molecular Biology and Genetics Department, Faculty of Arts and Sciences, Uşak University, 64300 Uşak, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Molecular Biology and Genetics Department, Faculty of Arts and Sciences, Uşak University, 64300 Uşak</wicri:regionArea>
<wicri:noRegion>64300 Uşak</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Konuk, Muhsin" sort="Konuk, Muhsin" uniqKey="Konuk M" first="Muhsin" last="Konuk">Muhsin Konuk</name>
<affiliation wicri:level="1"><nlm:aff id="Aff3">Molecular Biology and Genetics Department, Faculty of Engineering and Natural Sciences, Üsküdar University, Altunizade, 34662 Istanbul, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Molecular Biology and Genetics Department, Faculty of Engineering and Natural Sciences, Üsküdar University, Altunizade, 34662 Istanbul</wicri:regionArea>
<wicri:noRegion>34662 Istanbul</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ci Erci,  Brahim Hakk" sort="Ci Erci,  Brahim Hakk" uniqKey="Ci Erci  " first=" Brahim Hakk" last="Ci Erci"> Brahim Hakk Ci Erci</name>
<affiliation wicri:level="1"><nlm:aff id="Aff4">Biology Department, Faculty of Arts and Sciences, Afyon Kocatepe University, 03200 Afyonkarahisar, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Biology Department, Faculty of Arts and Sciences, Afyon Kocatepe University, 03200 Afyonkarahisar</wicri:regionArea>
<wicri:noRegion>03200 Afyonkarahisar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benouareth, Djameleddine" sort="Benouareth, Djameleddine" uniqKey="Benouareth D" first="Djameleddine" last="Benouareth">Djameleddine Benouareth</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma</wicri:regionArea>
<wicri:noRegion>24000 Guelma</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tabet, Mouna" sort="Tabet, Mouna" uniqKey="Tabet M" first="Mouna" last="Tabet">Mouna Tabet</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma</wicri:regionArea>
<wicri:noRegion>24000 Guelma</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Abda, Ahlem" sort="Abda, Ahlem" uniqKey="Abda A" first="Ahlem" last="Abda">Ahlem Abda</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma</wicri:regionArea>
<wicri:noRegion>24000 Guelma</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24363168</idno>
<idno type="pmc">4329306</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329306</idno>
<idno type="RBID">PMC:4329306</idno>
<idno type="doi">10.1007/s10616-013-9675-y</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">000089</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000089</idno>
<idno type="wicri:Area/Pmc/Curation">000088</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000088</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000194</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000194</idno>
<idno type="wicri:Area/Ncbi/Merge">000287</idno>
<idno type="wicri:Area/Ncbi/Curation">000287</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000287</idno>
<idno type="wicri:doubleKey">0920-9069:2013:Khallef M:genotoxicity:of:drinking</idno>
<idno type="wicri:Area/Main/Merge">000227</idno>
<idno type="wicri:Area/Main/Curation">000226</idno>
<idno type="wicri:Area/Main/Exploration">000226</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both <italic>Allium</italic>
 anaphase-telophase and comet tests</title>
<author><name sortKey="Khallef, Messaouda" sort="Khallef, Messaouda" uniqKey="Khallef M" first="Messaouda" last="Khallef">Messaouda Khallef</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1">Biochemistry Department, Faculty of Sciences, Badji Mokhtar University, 23000 Annaba, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biochemistry Department, Faculty of Sciences, Badji Mokhtar University, 23000 Annaba</wicri:regionArea>
<wicri:noRegion>23000 Annaba</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liman, Recep" sort="Liman, Recep" uniqKey="Liman R" first="Recep" last="Liman">Recep Liman</name>
<affiliation wicri:level="1"><nlm:aff id="Aff2">Molecular Biology and Genetics Department, Faculty of Arts and Sciences, Uşak University, 64300 Uşak, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Molecular Biology and Genetics Department, Faculty of Arts and Sciences, Uşak University, 64300 Uşak</wicri:regionArea>
<wicri:noRegion>64300 Uşak</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Konuk, Muhsin" sort="Konuk, Muhsin" uniqKey="Konuk M" first="Muhsin" last="Konuk">Muhsin Konuk</name>
<affiliation wicri:level="1"><nlm:aff id="Aff3">Molecular Biology and Genetics Department, Faculty of Engineering and Natural Sciences, Üsküdar University, Altunizade, 34662 Istanbul, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Molecular Biology and Genetics Department, Faculty of Engineering and Natural Sciences, Üsküdar University, Altunizade, 34662 Istanbul</wicri:regionArea>
<wicri:noRegion>34662 Istanbul</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ci Erci,  Brahim Hakk" sort="Ci Erci,  Brahim Hakk" uniqKey="Ci Erci  " first=" Brahim Hakk" last="Ci Erci"> Brahim Hakk Ci Erci</name>
<affiliation wicri:level="1"><nlm:aff id="Aff4">Biology Department, Faculty of Arts and Sciences, Afyon Kocatepe University, 03200 Afyonkarahisar, Turkey</nlm:aff>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Biology Department, Faculty of Arts and Sciences, Afyon Kocatepe University, 03200 Afyonkarahisar</wicri:regionArea>
<wicri:noRegion>03200 Afyonkarahisar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benouareth, Djameleddine" sort="Benouareth, Djameleddine" uniqKey="Benouareth D" first="Djameleddine" last="Benouareth">Djameleddine Benouareth</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma</wicri:regionArea>
<wicri:noRegion>24000 Guelma</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tabet, Mouna" sort="Tabet, Mouna" uniqKey="Tabet M" first="Mouna" last="Tabet">Mouna Tabet</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma</wicri:regionArea>
<wicri:noRegion>24000 Guelma</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Abda, Ahlem" sort="Abda, Ahlem" uniqKey="Abda A" first="Ahlem" last="Abda">Ahlem Abda</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma, Algeria</nlm:aff>
<country xml:lang="fr">Algérie</country>
<wicri:regionArea>Biology Department, Faculty of Natural Sciences, 8 Mai 1945 University, 24000 Guelma</wicri:regionArea>
<wicri:noRegion>24000 Guelma</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Cytotechnology</title>
<idno type="ISSN">0920-9069</idno>
<idno type="eISSN">1573-0778</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Genotoxic effects of bromoform and chloroform, disinfection by-products of the chlorination of drinking water, were examined by using mitotic index (MI), mitotic phase, chromosome aberrations (CAs) and comet assay on root meristematic cells of <italic>Allium cepa.</italic>
 Different concentrations of bromoform (25, 50, 75 and 100 μg/mL) and chloroform (25, 50, 100 and 200 μg/mL) were introduced to onion tuber roots. Distilled water was used as a negative control and methyl methansulfonate (MMS-10 μg/mL) as positive control. All obtained data were subjected to statistical analyses by using SPSS 15.0 for Windows software. For comparison purposes, Duncan multiple range tests by using one-way analysis of variance were employed and <italic>p</italic>
 < 0.05 was accepted as significant value. Exposure of both chemicals (except 25 μg/mL applications of bromoform) significantly decreased MI. Bromoform and chloroform (except 25 μg/mL applications) increased total CAs in <italic>Allium</italic>
 anaphase-telophase test. A significant increase in DNA damage was also observed at all concentrations of both bromoform and chloroform examined by comet assay. The damages were higher than that of positive control especially at 75–100 μg/mL for bromoform and 100–200 μg/mL for chloroform.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Algérie</li>
<li>Turquie</li>
</country>
</list>
<tree><country name="Algérie"><noRegion><name sortKey="Khallef, Messaouda" sort="Khallef, Messaouda" uniqKey="Khallef M" first="Messaouda" last="Khallef">Messaouda Khallef</name>
</noRegion>
<name sortKey="Abda, Ahlem" sort="Abda, Ahlem" uniqKey="Abda A" first="Ahlem" last="Abda">Ahlem Abda</name>
<name sortKey="Benouareth, Djameleddine" sort="Benouareth, Djameleddine" uniqKey="Benouareth D" first="Djameleddine" last="Benouareth">Djameleddine Benouareth</name>
<name sortKey="Tabet, Mouna" sort="Tabet, Mouna" uniqKey="Tabet M" first="Mouna" last="Tabet">Mouna Tabet</name>
</country>
<country name="Turquie"><noRegion><name sortKey="Liman, Recep" sort="Liman, Recep" uniqKey="Liman R" first="Recep" last="Liman">Recep Liman</name>
</noRegion>
<name sortKey="Ci Erci,  Brahim Hakk" sort="Ci Erci,  Brahim Hakk" uniqKey="Ci Erci  " first=" Brahim Hakk" last="Ci Erci"> Brahim Hakk Ci Erci</name>
<name sortKey="Konuk, Muhsin" sort="Konuk, Muhsin" uniqKey="Konuk M" first="Muhsin" last="Konuk">Muhsin Konuk</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/CobaltMaghrebV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000226 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000226 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Terre
   |area=    CobaltMaghrebV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4329306
   |texte=   Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:24363168" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CobaltMaghrebV1

This area was generated with Dilib version V0.6.32.
Data generation: Tue Nov 14 12:56:51 2017. Site generation: Mon Feb 12 07:59:49 2024

Serveur d'exploration sur le cobalt au Maghreb

Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests

Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le cobalt au Maghreb
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.